Figure 6

D1 receptor agonist-induced disruption of prepulse inhibition in nNOS KO mice. Startle responses at 110 dB and 120 dB were recorded (A). Startle response following 74 dB and 78 dB prepulse inhibition stimuli were recorded (B). Effect of SKF81297 administration on startle responses and prepulse inhibition in wild-type mice (C, D) and in nNOS KO mice (E, F). The p values indicate genotype effect (A, B) and drug effect (C-F) in repeated measures ANOVA.