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Figure 4 | Molecular Brain

Figure 4

From: ESCRT-III subunits Snf7-1 and Snf7-2 differentially regulate transmembrane cargos in hESC-derived human neurons

Figure 4

Both hSnf7-1 and hSnf7-2 are essential for the survival of human neurons. Terminally differentiated human neurons (14-16 DIV) were infected with lentivirus expressing either hSnf7-1 or hSnf7-2 siRNA. (A) Western blot analysis showed hSnf7-1 and hSnf7-2 specifically their expression. (B) Infection of lentivirus expressing either hSnf7-1 or hSnf7-2 siRNA caused human neuronal cell loss, respectively. GFP-positive and PI-negative neurons were considered as surviving neurons.

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Molecular Brain

ISSN: 1756-6606