Fig. 1
From: A protein phosphatase 2A deficit in the hippocampal CA1 area impairs memory extinction
PP2A-specific knockout efficiency. a Photo of Cont and CKO mice at 2 months old. b The genotype of the mice. The mouse who had both two kinds of sequences was identified as conditioned knockout (CKO), and the genotype of those had loxP sequences only was identified as control (Cont). c Western blot analysis of hippocampus tissue from Cont and CKO mice. There was no difference in other tissue without CA1 area of hippocampus (Hip-others) in both genotype of mice. But PP2A CKO mice showed a significance decrease expression of PP2A in CA1 region of hippocampus (Hip-CA1). d Immunohistochemistry with the PP2A C subunit antibody to confirm specific knockout of PP2A within the CA1 region of the hippocampus in CKO mice. Scale bar of (× 10) represents 50 μm; scale bar of (× 20) represents 100 μm