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Fig. 1 | Molecular Brain

Fig. 1

From: Aβ42 treatment of the brain side reduced the level of flotillin from endothelial cells on the blood side via FGF-2 signaling in a blood–brain barrier model

Fig. 1

A, B Schematic diagram of the in vitro BBB model comprising brain endothelial cells and astrocytes. In the in vitro BBB model, an insert membrane was used to construct the BBB, and brain endothelial cells were seeded onto the upper surface of the insert membrane, and astrocytes were seeded on the bottom of the wells. The upper side was taken to be the “blood side”, and the bottom side was taken to be the “brain side”. C Effects of Aβ on the TEER values in the in vitro BBB model. Statistical significance was calculated using one-way analysis of variance (ANOVA) and the Tukey test

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Molecular Brain

ISSN: 1756-6606