Fig. 3

Interacting circRNA-miRNA, miRNA-mRNA, circRNA-mRNA pairs and circRNA-miRNA-mRNA networks (A): CircRNA-miRNA pairs, in which circRNAs were all down-regulated, and miRNAs were up-regulated. (B): MiRNA-mRNA pairs, in which miRNAs were all up-regulated, and mRNAs were down-regulated. (C): CircRNA-mRNA pairs, in which circRNAs and mRNAs were all down-regulated. (D): CircRNA-miRNA-mRNA networks. Green represents circRNAs, red represents miRNAs, and yellow indicates mRNAs. DE: differentially expressed