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Fig. 2 | Molecular Brain

Fig. 2

From: γ-Aminobutyric acid type A receptor β1 subunit gene polymorphisms are associated with the sedative and amnesic effects of midazolam

Fig. 2

Manhattan plots of the genome-wide association analyses of the Ramsay sedation score in (a) the additive model, (b) the dominant model and (c) the recessive model. The − log10(P) values are plotted for all variants across the chromosomes. The blue lines indicate the genome-wide significance threshold (P = 0.05/314,404 [1.59 × 10− 7] in the additive model; P = 0.05/299,753 [1.67 × 10− 7] in the dominant and recessive models). Chromosome 0 indicates unmapped or multiple mapped single-nucleotide polymorphisms based on Genome Reference Consortium Human Build 38. XY, pseudoautosomal region; MT, mitochondrial DNA

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Molecular Brain

ISSN: 1756-6606