Skip to main content

Table 1 Patient characteristics

From: γ-Aminobutyric acid type A receptor β1 subunit gene polymorphisms are associated with the sedative and amnesic effects of midazolam

Age, yr (range)

37 (20‒60)

Sex, male/female

77/114

Height, cm

164 ± 9

Weight, kg

59 ± 12

BMI, kg m− 2

21.8 ± 3.6

ASA physical status, I/II

118/73

Type of dental procedure, n (%)

 

 Oral surgery

153 (80)

 Dental restoration

33 (17)

 Prosthodontics

5 (3)

Indications for sedation, n (%)

 

 Deeply impacted third molar extraction

69 (36)

 Dental phobia

67 (35)

 Gagging problem

35 (18)

 History of vasovagal reflex

11 (6)

 Other

9 (5)

Duration of procedure, min

33 ± 21

Duration of sedation, min

47 ± 21

Additional midazolam use, n (%)

93 (49)

Total midazolam dose, mg

3.5 ± 0.9

Propofol use, n (%)

121 (63)

Total propofol dose, mg

106 ± 82

MAP, mm Hg

 

 Baseline

92.3 ± 15.3

 After midazolam dose

84.0 ± 12.2

Pulse rate, beats min− 1

 

 Baseline

79.4 ± 14.5

 After midazolam dose

82.4 ± 13.1

SpO2, %

 

 Baseline

98.5 ± 1.3

 After midazolam dose

96.6 ± 2.0

BIS value

 

 Baseline

96.3 ± 2.8

 After midazolam dose

76.7 ± 8.1

Ramsay sedation scale, n (%)

 

 Score 1

14 (7)

 Score 2

43 (22)

 Score 3

57 (30)

 Score 4

51 (27)

 Score 5

23 (12)

 Score 6

3 (2)

Presence of amnesia, n (%)

132 (69)

Adverse events, n (%)

 

 Airway obstruction

25 (13)

 Transient apnea

4 (2)

 Desaturation

14 (7)

  1. The data are expressed as mean ± SD or number (%). The Ramsay sedation score was recorded 5 min after the initial midazolam administration. BMI, body mass index; ASA, American Society of Anesthesiologists; MAP, mean arterial pressure; BIS, Bispectral index