Skip to main content
Fig. 8 | Molecular Brain

Fig. 8

From: Chronic corticosterone exposure causes anxiety- and depression-related behaviors with altered gut microbial and brain metabolomic profiles in adult male C57BL/6J mice

Fig. 8

Brain and plasma metabolites in mice chronically treated with corticosterone. a Brain and plasma metabolites related to neurotransmission in CORT- and Veh-treated mice. b, e, h Principal component analysis (PCA) score plots of metabolomic data in CORT- and Veh-treated mice. c, f, i Partial least squares discriminant analysis (PLS-DA) score plots of metabolomic data. d, g, j Enrichment analysis of metabolites with a VIP value of > 1 in PLS-DA and p-value of < 0.05 in the t-test for comparisons between CORT- and Veh-treated mice. b–d Medial prefrontal cortex (mPFC). e–g Habenula/paraventricular nucleus of the thalamus (Hb/PVT). h–j Plasma. *p < 0.05

Back to article page

Molecular Brain

ISSN: 1756-6606