Fig. 5
From: NEK7 induces lactylation in Alzheimer’s disease to promote pyroptosis in BV-2 cells
Lactylation of BV-2 cells is related to NEK7. (A) Protein levels of lactylation under Aβ treatment evaluated by Western blotting. (B) Interaction between the NEK7 promoter and H4K12la assessed by ChIP-PCR. (C) mRNA expression of NEK7 in BV-2 cells transfected with si-LDHA. (D) NEK7 transcriptional activity in BV-2 cells transfected with si-LDHA. (E) mRNA expression of NEK7 in BV-2 cells transfected with si-LDHA evaluated by qRT-PCR. (F) Protein expression of NEK7 in BV-2 cells transfected with si-LDHA evaluated by Western blotting