Fig. 6

NSG KO animals display enhanced recall in Morris Water Maze. (A) Animals from both groups showed similar reductions in duration to find the hidden platform during six training trials with no differences between wt and KO (p = 0.97). (B) Time spent in the target vs. non-target quadrant for each animal is shown for probe trials with hidden platform removed. Dotted line represents 25% of the total time, which is equivalent to chance. cued (right) trials. Wild-type animals did not significantly differ between time spent in the Target and non-target quadrants (p = 0.62) while NSG2 KO animals spent significantly more time in the target quadrant relative to the non-target quadrant (B; p = 0.001). (C) No differences were detected between groups for latency to find the visible platform during the cued trial (p = 0.32)