Fig. 7

NSG2 KO animals display accelerated fear learning and augmented associative memory. (A-B) Percentage of time spent freezing during the tone period (A) and trace period (B) is illustrated across five acquisition trials for both wt and NSG2 KO mice. Compared to wt mice, NSG2 mutants exhibited significantly increased freezing times during the training period (p < 0.02). (C) NSG2 KO animals also displayed greater freezing behavior during the tone period (p < 0.05) when presented in a different chamber 24 h following training but without footshock stimuli. (D) No differences were observed between groups during the trace period when presented in a different chamber 24 h following training but without footshock stimuli (p > 0.05). Results are expressed as mean ± SEM. n = 12/genotype