Fig. 8
From: Quercetin carbon quantum dots: dual-target therapy for intracerebral hemorrhage in mice
QECQDs treatment alleviates brain injury and enhances neurological function following ICH. (a) Schematic diagram of brain injury assessment process following intrathecal injection of QECQDs in the ICH mouse model. (b, c) Representative images (b) and quantitative analysis (c) of brain hematoma volume reduction on day 3 post-QECQDs treatment (n = 7/group, one-way ANOVA). Scale bar represents 1 mm. (d) Quantitative analysis of brain tissue water content changes on days 1, 3, 5, and 7 post-QECQDs treatment in the ipsilateral hemisphere (n = 7/group, one-way ANOVA). (e) Schematic diagram of neurological function assessment process following intrathecal injection of QECQDs in the ICH mouse model. (f) mNSS functional assessment at different time points (days 1, 3, 5, and 7) post-QECQDs intervention (n = 7/group, one-way ANOVA). (g, h) Evaluation of forelimb grip strength (g) and left hind limb pain threshold changes (h) at different time points (days 1, 3, 5, and 7) post-treatment with QECQDs (n = 5/group, one-way ANOVA)