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Fig. 4 | Molecular Brain

Fig. 4

From: Dynamic changes in the hippocampal neuronal circuits activity following acute stress revealed by miniature fluorescence microscopy imaging

Fig. 4

Pairwise correlation properties stay stable while percent of co-active neurons elevates after acute stress. a Pearson’s correlation coefficient value for all states with preset threshold values calculated by “spike” method. b Pearson’s correlation coefficient value for all states with preset threshold values calculated by “full” method. c Number of connected pairs of neurons in relation to all the pairs with preset threshold (threshold = 0; baseline (n = 15) vs 3 h (n = 3): p = 0.012, Kruskal–Wallis test following Dunn’s test for multiple comparison). d Number of connected pairs of neurons as a fraction from all pairs with preset threshold. Network degree (e) right after stress (baseline (n = 15) vs stress (n = 3), threshold: 0.00: p = 0.0473; 0.05: p = 0.0156; 0.10: p = 0.0091; 0.15: p = 0.0098; 0.20: p = 0.0118; 0.25: p = 0.0158; 0.30: p = 0.0175; Student’s t-test for all). f 3 h post acute stress (baseline (n = 15) vs 3 h (n = 3), threshold: 0.00: p = 0.0155; 0.05: p = 0.0132; 0.10: p = 0.0167; 0.15: p = 0.0277; 0.20: p = 0.0460; 0.25: p = 0.0688; 0.30: p = 0.100, Student’s t-test for all). g 10 days post acute stress (all differences are non-significant, Student’s t-test). ns-non-significant; #: p < 0.05; #: *: p < 0.05; **: p < 0.01. All the data presented as mean ± SEM. For e, f and g dotted line represents threshold level for “strongly” correlated units

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