Fig. 3

MR association of genetically determined T/E2 ratio with stroke subtypes. MR, Mendelian randomization; T/E2, testosterone/17β-estradiol; AIS, any ischemic stroke; LAS, large artery stroke; CES, cardioembolic stroke; SVS, small vessel stroke; ICH, intracerebral hemorrhage; SAH, subarachnoid hemorrhage; SNPs, single nucleotide polymorphisms; IVW, inverse variance weighted; OR, odd ratio; CI, confidence interval