Fig. 1

Anti-pruritic effects of terpenes injected subcutaneously in mouse models of histaminergic and non-histaminergic itch. Time scratching after different doses of (a) camphene or (b) alpha-bisabolol in histamine model. Time scratching with and without camphene (c) or alpha-bisabolol (d) at 100 µg (s.c.) in the chloroquine model. Each bar represents the mean ± S.E.M (n = 5–6). **p < 0.01, ***p < 0.001, ns = no significance. Panels a and b were analyzed by One-way ANOVA followed by a Tukey’s test. Panels c and d were analyzed by unpaired t-test