Fig. 3
From: GAS reduced inflammatory responses in activated microglia by regulating the Ccr2/Akt/Gsk-3β pathway
GAS inhibits Ccr2 expression and increased the Akt and Gsk-3β phosphorylation in HIBD mice. A Confocal microscope images show the co-localization of Ccr2, p-Akt, p-Gsk-3β (red) in Lectin + microglia cells (green) at 1 day after HIBD. B Presents the average immunofluorescence values of Ccr2, p-Akt, and p-Gsk-3β at 1 day after HIBD. C Confocal microscope images show the co-localization of Ccr2, p-Akt, p-Gsk-3β (red) in Lectin + microglia cells (green) at 3 days after HIBD. D Presents the average immunofluorescence values of Ccr2, p-Akt, and p-Gsk-3β at 3 days after HIBD. n = 3, *P < 0.05, **P < 0.01, ***P < 0.001. Scale: 50 μm