Fig. 1
From: Post-conditioning sleep deprivation facilitates delay and trace fear memory extinction
Protocols for delay and trace fear conditioning, followed by recall and extinction sessions. (A) In delay fear conditioning, an electrical foot shock was paired with the end of each CS+ (30 s, 10 kHz), while CS- (30 s, 2 kHz) was presented without a foot shock. In trace fear conditioning, the foot shock was delivered 20 s after the CS+ (30 s, 10 kHz). (B) Following auditory fear conditioning on Day 1, male and female mice were re-exposed to tone stimuli without the foot shock for Extinction #1 on Day 2, the Remote recall on Day 17, and Extinction #2 on Day 18. A subset of mice underwent 6-hour SD after auditory fear conditioning