Fig. 5
From: Post-conditioning sleep deprivation facilitates delay and trace fear memory extinction
Post-conditioning SD gradually enhanced delay fear extinction, independent of pre-existing group differences. (A, B) Scatter plots and linear regression lines representing freezing behavior in male (A) and female (B) mice during each set of CS+ recall trials compared to conditioning on Day 1. Group differences between S and SD were tested while accounting for freezing on Day 1 as a covariate (ANCOVA, *p < 0.05, **p < 0.01, Table 3). Each set of re-exposure corresponds to early Day 2 (A1, B1), late Day 2 (A2, B2), Day 17 (A3, B3), early Day 18 (A4, B4), and late Day 18 (A5, B5). SD decreased freezing during Remote recall in male mice (A3) and during Remote recall (B3) and early Extinction #2 (B4) in female mice